Table of Contents
OVERVIEW OF MITOCHONDRIA. Metabolism of Superoxide Radical and Hydrogen Peroxide in the Mitochondria. Energy-Redox Axis in Mitochondria: Interconnection of Energy-Transducing Capacity and Redox Status. Signal Transduction Pathways That Regulate Mitochondrial Gene Expression. Transcriptional Regulation of Mitochondrial Biogenesis and Quality Control. Mitochondria in Liver Disease: Regulation of Liver Mitochondrial Function by Hydrogen Sulfide. Impact of Aging and Calorie Restriction on Liver Mitochondria. Drug Delivery to Mitochondria: A Promising Approach for the Treatment of Liver Disease. ROLE OF MITOCHONDRIA IN LIVER DISEASES. Central Role of Mitochondria in Drug-Induced Liver Injury. Role of Autophagy and Mitophagy in Liver Diseases. Mitochondrial Dynamics, Mitophagy and Mitochondrial Spheroids in Drug-Induced Liver Injury. Biomarkers of Mitochondrial Damage in the Liver. Alterations of Mitochondrial DNA in Liver Diseases. Epigenetic Modifications of Mitochondrial DNA in Liver Disease: Focus on Nonalcoholic Fatty Liver Disease. Emerging Role of Mitochondrial Dynamics in Viral Hepatitis. Mitochondrial Dynamics and Liver Metabolism. Role of JNK in Lipotoxicity in the Liver. Mitochondrial Function, Dysfunction, and Adaptation in the Liver during the Development of Diabetes. Mitochondrial Dynamics and Adaptation in Alcoholic Liver Disease and Nonalcoholic Fatty Liver Disease. Acid Sphingomyelinase, Mitochondria, and Liver Diseases. Regulation of Liver Metabolism by Sirtuins: Emerging Roles.