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Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers

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145,59 138,31

Autor: Necchi, A
Editor: SPRINGER
Edición: 1
Páginas: 299
Año edición: 2022
SKU: 9783030805456 Categories ,

CONTENTS  :

Introduction.- State-of-the art and ongoing developments.- Clinical cases debate: neoadjuvant checkpoint inhibition vs standard chemotherapy.- Slideshow of tumor samples before and after checkpoint inhibition.- Ongoing trials and clinical trials endpoints debate: the role of pathological response as a surrogate of survival endpoints.- State-of-the-art and future role of molecular biomarkers for patient selection.- Background of immunotherapy trials in prostate cancer.- Clinical case debate: immunotherapy vs alternative therapies in the neoadjuvant and adjuvant setting of localized, high-risk prostate cancer.- Cytoreductive nephrectomy in the era of targeted therapy and immunotherapy.- Clinical cases debate: Neoadjuvant vs adjuvant immunotherapy in localized RCC.- Benchmark of surgical safety results.- What the scientific data tell us about predictive biomarkers of immunotherapy efficacy across the GU malignancies.- Clinical cases debate: biomarker-driven patient selection vs unselective perioperative strategies.

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